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Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

BACKGROUND: Both the parasympathetic and sympathetic nervous system exert control over innate immune responses. In inflammatory bowel disease, sympathetic innervation in intestinal mucosa is reduced. Our aim was to investigate the role of sympathetic innervation to the intestine on regulation of the...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Willemze, Rose A., Welting, Olaf, van Hamersveld, Patricia, Verseijden, Caroline, Nijhuis, Laurens E., Hilbers, Francisca W., Meijer, Sybren L., Heesters, Balthasar A., Folgering, Joost H. A., Darwinkel, Harold, Blancou, Philippe, Vervoordeldonk, Margriet J., Seppen, Jurgen, Heinsbroek, Sigrid E. M., de Jonge, Wouter J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322236/
https://ncbi.nlm.nih.gov/pubmed/30616543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0068-8
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