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Evidence-based sizing of non-inferiority trials using decision models
BACKGROUND: There are significant challenges to the successful conduct of non-inferiority trials because they require large numbers to demonstrate that an alternative intervention is “not too much worse” than the standard. In this paper, we present a novel strategy for designing non-inferiority tria...
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| Pubblicato in: | BMC Med Res Methodol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322228/ https://ncbi.nlm.nih.gov/pubmed/30612554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-018-0643-2 |
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