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Impact of Replication Stress in Human Papillomavirus Pathogenesis
The inactivation of critical cell cycle checkpoints by the human papillomavirus (HPV) oncoprotein E7 results in replication stress (RS) that leads to genomic instability in premalignant lesions. Intriguingly, RS tolerance is achieved through several mechanisms, enabling HPV to exploit the cellular R...
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| Published in: | J Virol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6321920/ https://ncbi.nlm.nih.gov/pubmed/30355682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01012-17 |
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