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Impact of Replication Stress in Human Papillomavirus Pathogenesis

The inactivation of critical cell cycle checkpoints by the human papillomavirus (HPV) oncoprotein E7 results in replication stress (RS) that leads to genomic instability in premalignant lesions. Intriguingly, RS tolerance is achieved through several mechanisms, enabling HPV to exploit the cellular R...

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Detalhes bibliográficos
Publicado no:J Virol
Autor principal: Moody, Cary A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Gem
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321920/
https://ncbi.nlm.nih.gov/pubmed/30355682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01012-17
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