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Cytomegalovirus Exposure in the Elderly Does Not Reduce CD8 T Cell Repertoire Diversity

With age, the immune system becomes less effective, causing increased susceptibility to infection. Chronic CMV infection further impairs immune function and is associated with increased mortality in the elderly. CMV exposure elicits massive CD8(+) T cell clonal expansions and diminishes the cytotoxi...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Lindau, Paul, Mukherjee, Rithun, Gutschow, Miriam V., Vignali, Marissa, Warren, Edus H., Riddell, Stanley R., Makar, Karen W., Turtle, Cameron J., Robins, Harlan S.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321841/
https://ncbi.nlm.nih.gov/pubmed/30541882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800217
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