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A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration

Cellular senescence is a major hurdle for primary cell-based tissue engineering and regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes and the loss of tumor suppressor genes all may account for the cellular senescence process with the involvement of various signal...

詳細記述

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書誌詳細
出版年:Cell Biosci
主要な著者: Wang, Yiming, Chen, Song, Yan, Zuoqin, Pei, Ming
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321683/
https://ncbi.nlm.nih.gov/pubmed/30627420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0264-9
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