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A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration

Cellular senescence is a major hurdle for primary cell-based tissue engineering and regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes and the loss of tumor suppressor genes all may account for the cellular senescence process with the involvement of various signal...

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Bibliografske podrobnosti
izdano v:Cell Biosci
Main Authors: Wang, Yiming, Chen, Song, Yan, Zuoqin, Pei, Ming
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321683/
https://ncbi.nlm.nih.gov/pubmed/30627420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0264-9
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