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Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9

Retinitis pigmentosa is the most common form of inherited blindness and can be caused by a multitude of different genetic mutations that lead to similar phenotypes. Specifically, mutations in ubiquitously expressed splicing factor proteins are known to cause an autosomal dominant form of the disease...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Foltz, Leah P., Howden, Sara E., Thomson, James A., Clegg, Dennis O.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321630/
https://ncbi.nlm.nih.gov/pubmed/30572641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19124127
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