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Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases
Ribonucleases are proteins whose use is promising in anticancer therapy. We have previously constructed different human pancreatic ribonuclease variants that are selectively cytotoxic for tumor cells by introducing a nuclear localization signal into their sequence. However, these modifications produ...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6321540/ https://ncbi.nlm.nih.gov/pubmed/30544927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123273 |
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