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Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces

Manufacturing parameters may have a strong impact on the dissolution and disintegration of solid dosage forms. In line with process analytical technology (PAT) and quality by design approaches, computer-based technologies can be used to design, control, and improve the quality of pharmaceutical comp...

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Опубликовано в: :Pharmaceutics
Главные авторы: Yokoyama, Reiji, Kimura, Go, Schlepütz, Christian M., Huwyler, Jörg, Puchkov, Maxim
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321502/
https://ncbi.nlm.nih.gov/pubmed/30513888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040259
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