Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model

Isoquercetin (IQ), a glucoside derivative of quercetin, has been reported to have beneficial effects in nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the potential improvement of IQ in liver lipid accumulation, inflammation, oxidative condition, and activation in Kupffer c...

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Publicado en:Int J Mol Sci
Autores principales: Qin, Guohong, Ma, Ji, Huang, Qiongshan, Yin, Hongli, Han, Jichun, Li, Maoru, Deng, Yang, Wang, Bing, Hassan, Waseem, Shang, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321444/
https://ncbi.nlm.nih.gov/pubmed/30572631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19124126
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