Current Landscape and the Potential Role of Hypoxia-Inducible Factors and Selenium in Clear Cell Renal Cell Carcinoma Treatment

In the last two decades, the discovery of various pathways involved in renal cell carcinoma (RCC) has led to the development of biologically-driven targeted therapies. Hypoxia-inducible factors (HIFs), angiogenic growth factors, von Hippel–Lindau (VHL) gene mutations, and oncogenic microRNAs (miRNAs...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Garje, Rohan, An, Josiah J., Sanchez, Kevin, Greco, Austin, Stolwijk, Jeffrey, Devor, Eric, Rustum, Youcef, Zakharia, Yousef
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321165/
https://ncbi.nlm.nih.gov/pubmed/30513765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123834
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