Current Landscape and the Potential Role of Hypoxia-Inducible Factors and Selenium in Clear Cell Renal Cell Carcinoma Treatment

In the last two decades, the discovery of various pathways involved in renal cell carcinoma (RCC) has led to the development of biologically-driven targeted therapies. Hypoxia-inducible factors (HIFs), angiogenic growth factors, von Hippel–Lindau (VHL) gene mutations, and oncogenic microRNAs (miRNAs...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Garje, Rohan, An, Josiah J., Sanchez, Kevin, Greco, Austin, Stolwijk, Jeffrey, Devor, Eric, Rustum, Youcef, Zakharia, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321165/
https://ncbi.nlm.nih.gov/pubmed/30513765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123834
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