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Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem(®)-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke

Ischemic stroke is a leading cause of death and disability worldwide. Potential therapeutics aimed at neural repair and functional recovery are limited in their blood-brain barrier permeability and may exert systemic or off-target effects. We examined the effects of brain-derived neurotrophic factor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ravina, Kristine, Briggs, Denise I., Kislal, Sezen, Warraich, Zuha, Nguyen, Tiffany, Lam, Rachel K., Zarembinski, Thomas I., Shamloo, Mehrdad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321015/
https://ncbi.nlm.nih.gov/pubmed/30486515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123782
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