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Effects of Toona sinensis Leaf Extract and Its Chemical Constituents on Xanthine Oxidase Activity and Serum Uric Acid Levels in Potassium Oxonate-Induced Hyperuricemic Rats

Toona sinensis leaf is used as a seasonal vegetable in Korea. A 70% ethanol extract of these leaves exhibited potent xanthine oxidase (XO) inhibition, with a 50% inhibitory concentration (IC(50)) of 78.4 µM. To investigate the compounds responsible for this effect, bioassay-guided purification led t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yuk, Heung Joo, Lee, Young-Sil, Ryu, Hyung Won, Kim, Seung-Hyung, Kim, Dong-Seon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321014/
https://ncbi.nlm.nih.gov/pubmed/30544886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123254
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