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Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics

(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases. One of the initial steps in the selection of an antibody candidate for further pre-clinical development is determining its pharmacokinetics in small...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Allen, Kevin J. H., Jiao, Rubin, Malo, Mackenzie E., Frank, Connor, Dadachova, Ekaterina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320949/
https://ncbi.nlm.nih.gov/pubmed/30563123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040262
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