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Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics

(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases. One of the initial steps in the selection of an antibody candidate for further pre-clinical development is determining its pharmacokinetics in small...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmaceutics
Prif Awduron: Allen, Kevin J. H., Jiao, Rubin, Malo, Mackenzie E., Frank, Connor, Dadachova, Ekaterina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320949/
https://ncbi.nlm.nih.gov/pubmed/30563123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040262
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