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Preparation and Characterization of Spherical Amorphous Solid Dispersion with Amphotericin B

In the present study, new polymer microspheres of amphotericin B (AmB) were prepared by a spray drying technique using cyclodextrin polymers (Poly-CD) to improve the solubility and dissolution of AmB, to prevent in vivo toxic AmB aggregations. Formulations were characterized through scanning electro...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Mehenni, Lyes, Lahiani-Skiba, Malika, Ladam, Guy, Hallouard, François, Skiba, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320868/
https://ncbi.nlm.nih.gov/pubmed/30453493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040235
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