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Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer

Demethoxycurcumin (DMC), through a self-assembled amphiphilic carbomethyl-hexanoyl chitosan (CHC) nanomatrix has been successfully developed and used as a therapeutic approach to inhibit cisplatin-induced drug resistance by suppressing excision repair cross-complementary 1 (ERCC1) in non-small cell...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Ying-Yi, Lin, Yu-Jung, Huang, Wei-Ting, Hung, Chin-Chuan, Lin, Hui-Yi, Tu, Yu-Chen, Liu, Dean-Mo, Lan, Shou-Jen, Sheu, Ming-Jyh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320861/
https://ncbi.nlm.nih.gov/pubmed/30563166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123217
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