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Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease

Sonic hedgehog (Shh) is a prototypical angiogenic agent with a crucial role in the regulation of angiogenesis. Experimental studies have shown that Shh is upregulated in response to ischemia. Also, Shh may be found on the surface of circulating microparticles (MPs) and MPs bearing Shh (Shh + MPs) ha...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Giarretta, Igor, Gatto, Ilaria, Marcantoni, Margherita, Lupi, Giulia, Tonello, Diego, Gaetani, Eleonora, Pitocco, Dario, Iezzi, Roberto, Truma, Addolorata, Porfidia, Angelo, Visonà, Adriana, Tondi, Paolo, Pola, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320804/
https://ncbi.nlm.nih.gov/pubmed/30544841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123954
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