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Sonic Hedgehog Therapy in a Mouse Model of Age-Associated Impairment of Skeletal Muscle Regeneration

Sonic hedgehog (Shh) is a morphogen regulating muscle development during embryogenesis. We have shown that the Shh pathway is postnatally recapitulated after injury and during regeneration of the adult skeletal muscle and regulates angiogenesis and myogenesis after muscle injury. Here, we demonstrat...

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Bibliografiska uppgifter
Huvudupphovsmän: Piccioni, Andrea, Gaetani, Eleonora, Neri, Valentina, Gatto, Ilaria, Palladino, Mariangela, Silver, Marcy, Smith, Roy C., Giarretta, Igor, Pola, Enrico, Hlatky, Lynn, Pola, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976139/
https://ncbi.nlm.nih.gov/pubmed/23781099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt076
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