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SeqClone: sequential Monte Carlo based inference of tumor subclones
BACKGROUND: Tumor samples are heterogeneous. They consist of varying cell populations or subclones and each subclone is characterized with a distinct single nucleotide variant (SNV) profile. This explains the source of genetic heterogeneity observed in tumor sequencing data. To make precise prognosi...
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| Published in: | BMC Bioinformatics |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6320595/ https://ncbi.nlm.nih.gov/pubmed/30611189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2562-y |
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