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A sequential Monte Carlo algorithm for inference of subclonal structure in cancer

Tumors are heterogeneous in the sense that they consist of multiple subpopulations of cells, referred to as subclones, each of which is characterized by a distinct profile of genomic variations such as somatic mutations. Inferring the underlying clonal landscape has become an important topic in that...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Ogundijo, Oyetunji E., Zhu, Kaiyi, Wang, Xiaodong, Anastassiou, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347199/
https://ncbi.nlm.nih.gov/pubmed/30682127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211213
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