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Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
Glycoconjugate vaccines are among the most effective interventions for preventing several serious infectious diseases. Covalent linkage of the bacterial capsular polysaccharide to a carrier protein provides CD4(+) T cells with epitopes that facilitate a memory response to the polysaccharide. Classic...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6320544/ https://ncbi.nlm.nih.gov/pubmed/30510007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816401115 |
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