Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides

Group B Streptococcus (GBS) causes serious infection in neonates and is an important target of vaccine development. Zwitterionic polysaccharides (ZPS), obtained through chemical introduction of positive charges into anionic polysaccharides (PS) from GBS, have the ability to activate human and mouse...

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Detalhes bibliográficos
Main Authors: Gallorini, Simona, Berti, Francesco, Mancuso, Giuseppe, Cozzi, Roberta, Tortoli, Marco, Volpini, Gianfranco, Telford, John L., Beninati, Concetta, Maione, Domenico, Wack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762674/
https://ncbi.nlm.nih.gov/pubmed/19805031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903313106
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