AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis

Advanced age and unhealthy dietary habits contribute to the increasing incidence of obesity and type 2 diabetes. These metabolic disorders, which are often accompanied by oxidative stress and compromised nitric oxide (NO) signaling, increase the risk of adverse cardiovascular complications and devel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cordero-Herrera, Isabel, Kozyra, Mikael, Zhuge, Zhengbing, McCann Haworth, Sarah, Moretti, Chiara, Peleli, Maria, Caldeira-Dias, Mayara, Jahandideh, Arghavan, Huirong, Han, Cruz, Josiane de Campos, Kleschyov, Andrei L., Montenegro, Marcelo F., Ingelman-Sundberg, Magnus, Weitzberg, Eddie, Lundberg, Jon O., Carlstrom, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320503/
https://ncbi.nlm.nih.gov/pubmed/30559212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809406115
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