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Widespread cumulative influence of small effect-size mutations on yeast quantitative traits

Quantitative traits are influenced by pathways that have traditionally been defined through genes that have a large loss- or gain-of-function effect. However, in theory, a large number of small effect-size genes could cumulatively play a substantial role in pathway function. Here, we determined the...

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Библиографические подробности
Опубликовано в: :Cell Syst
Главные авторы: Hua, Bo, Springer, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319666/
https://ncbi.nlm.nih.gov/pubmed/30579728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.11.004
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