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Widespread cumulative influence of small effect-size mutations on yeast quantitative traits

Quantitative traits are influenced by pathways that have traditionally been defined through genes that have a large loss- or gain-of-function effect. However, in theory, a large number of small effect-size genes could cumulatively play a substantial role in pathway function. Here, we determined the...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Hua, Bo, Springer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319666/
https://ncbi.nlm.nih.gov/pubmed/30579728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.11.004
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