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Cerebrospinal fluid biomarkers of central dopamine deficiency predict Parkinson’s disease
BACKGROUND: Consistent with nigrostriatal dopamine depletion, low cerebrospinal fluid (CSF) concentrations of 3,4-dihydroxyphenylacetic acid (DOPAC), the main neuronal metabolite of dopamine, characterizes Parkinson’s disease (PD) even in recently diagnosed patients. Whether low CSF levels of DOPAC...
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| Publié dans: | Parkinsonism Relat Disord |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319386/ https://ncbi.nlm.nih.gov/pubmed/29475591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2018.02.023 |
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