miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and Cardiotoxicity

Improved therapy of cancer has significantly increased the lifespan of patients. However, cancer survivors face an increased risk of cardiovascular complications due to adverse effects of cancer therapies. The chemotherapy drug doxorubicin is well known to induce myofibril damage and cardiac atrophy...

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Vydáno v:Mol Ther
Hlavní autoři: Gupta, Shashi Kumar, Garg, Ankita, Avramopoulos, Petros, Engelhardt, Stefan, Streckfuss-Bömeke, Katrin, Batkai, Sandor, Thum, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319305/
https://ncbi.nlm.nih.gov/pubmed/30527757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.004
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