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A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation
Induction of interferons during viral infection is mediated by cellular proteins that recognise viral nucleic acids. MDA5 is one such sensor of virus presence and is activated by RNA. MDA5 is required for immunity against several classes of viruses, including picornaviruses. Recent work showed that...
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| Publicado no: | Trends Microbiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Authors. Published by Elsevier Ltd.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319154/ https://ncbi.nlm.nih.gov/pubmed/30201512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2018.08.007 |
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