Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism

Previously, we proposed the following mechanism for konjac ceramide (kCer)-mediated neurite outgrowth inhibition: kCer binds to Nrp as a Sema3A agonist, resulting in Nrp1/PlexA complex formation and activation of the Sema3A signaling pathway to induce phosphorylation of CRMP2 and microtubule depolym...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Usuki, Seigo, Tamura, Noriko, Tamura, Tomohiro, Higashiyama, Shigeki, Tanji, Kunikazu, Mitsutake, Susumu, Inoue, Asuka, Aoki, Junken, Mukai, Katsuyuki, Igarashi, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319021/
https://ncbi.nlm.nih.gov/pubmed/30623117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.11.004
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