High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

BACKGROUND: Neuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their own cancer stem cells (CSC). There is evidence indicating that CSC may be responsible for tumour progression, chemotherapy resistance and recurrence in NBTs. Oct4 is a t...

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Vydáno v:BMC Cancer
Hlavní autoři: Monferrer, Ezequiel, Burgos-Panadero, Rebeca, Blanquer-Maceiras, Maite, Cañete, Adela, Navarro, Samuel, Noguera, Rosa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318846/
https://ncbi.nlm.nih.gov/pubmed/30606139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5219-3
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