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High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

BACKGROUND: Neuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their own cancer stem cells (CSC). There is evidence indicating that CSC may be responsible for tumour progression, chemotherapy resistance and recurrence in NBTs. Oct4 is a t...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Monferrer, Ezequiel, Burgos-Panadero, Rebeca, Blanquer-Maceiras, Maite, Cañete, Adela, Navarro, Samuel, Noguera, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318846/
https://ncbi.nlm.nih.gov/pubmed/30606139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5219-3
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