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Liver iron sensing and body iron homeostasis

The liver orchestrates systemic iron balance by producing and secreting hepcidin. Known as the iron hormone, hepcidin induces degradation of the iron exporter ferroportin to control iron entry into the bloodstream from dietary sources, iron recycling macrophages, and body stores. Under physiologic c...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Wang, Chia-Yu, Babitt, Jodie L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318427/
https://ncbi.nlm.nih.gov/pubmed/30401708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-815894
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