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Liver iron sensing and body iron homeostasis
The liver orchestrates systemic iron balance by producing and secreting hepcidin. Known as the iron hormone, hepcidin induces degradation of the iron exporter ferroportin to control iron entry into the bloodstream from dietary sources, iron recycling macrophages, and body stores. Under physiologic c...
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| Udgivet i: | Blood |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6318427/ https://ncbi.nlm.nih.gov/pubmed/30401708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-06-815894 |
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