Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens

The study of pathophysiological mechanisms in human liver disease has been constrained by the inability to expand primary hepatocytes in vitro while maintaining proliferative capacity and metabolic function. We and others have previously shown that mouse mature hepatocytes can be converted to liver...

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Vydáno v:Cell Res
Hlavní autoři: Fu, Gong-Bo, Huang, Wei-Jian, Zeng, Min, Zhou, Xu, Wu, Hong-Ping, Liu, Chang-Cheng, Wu, Han, Weng, Jun, Zhang, Hong-Dan, Cai, Yong-Chao, Ashton, Charles, Ding, Min, Tang, Dan, Zhang, Bao-Hua, Gao, Yi, Yu, Wei-Feng, Zhai, Bo, He, Zhi-Ying, Wang, Hong-Yang, Yan, He-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318298/
https://ncbi.nlm.nih.gov/pubmed/30361550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0103-x
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