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Endothelial Cells Promote Colorectal Cancer Cell Survival by Activating the HER3-AKT Pathway in a Paracrine Fashion

The regulation of colorectal cancer (CRC) cell survival pathways remains to be elucidated. Previously it was demonstrated that endothelial cells (ECs) from the liver (liver parenchymal ECs or LPECs), the most common site of CRC metastases, secrete soluble factors in the conditioned medium (CM) that,...

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Библиографические подробности
Опубликовано в: :Mol Cancer Res
Главные авторы: Wang, Rui, Bhattacharya, Rajat, Ye, Xiangcang, Fan, Fan, Boulbes, Delphine R., Ellis, Lee M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318043/
https://ncbi.nlm.nih.gov/pubmed/30131447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0341
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