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Immunoregulatory Protein B7-H3 Regulates Cancer Stem Cell Enrichment and Drug Resistance through MVP-mediated MEK Activation

B7-H3 is a tumor promoting glycoprotein that is expressed at low levels in most normal tissues but is overexpressed in various human cancers which is associated with disease progression and poor patient outcome. Although numerous publications have reported the correlation between B7-H3 and cancer pr...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Liu, Zixing, Zhang, Wenling, Phillips, Joshua B., Arora, Ritu, McClellan, Steven, Li, Jiangfeng, Kim, Jin-Hwan, Sobol, Robert W., Tan, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318029/
https://ncbi.nlm.nih.gov/pubmed/30082909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0407-9
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