Metabolic reprogramming by the S-nitroso-CoA Reductase system protects from kidney injury

Endothelial nitric oxide (NO) synthase (eNOS) is protective against kidney injury, but the molecular mechanisms are poorly understood(1,2). NO-based cellular signaling is generally mediated by protein S-nitrosylation, the oxidative modification of Cys residues to form S-nitrosothiols (SNOs). S-nitro...

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Publicado no:Nature
Main Authors: Zhou, Hua-Lin, Zhang, Rongli, Anand, Puneet, Stomberski, Colin T., Qian, Zhaoxia, Hausladen, Alfred, Wang, Liwen, Rhee, Eugene P., Parikh, Samir M., Karumanchi, S. Ananth, Stamler, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318002/
https://ncbi.nlm.nih.gov/pubmed/30487609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0749-z
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