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Electrostatic control of calcineurin’s intrinsically-disordered regulatory domain binding to calmodulin
Calcineurin (CaN) is a serine/threonine phosphatase that regulates a variety of physiological and pathophysiological processes in mammalian tissue. The calcineurin (CaN) regulatory domain (RD) is responsible for regulating the enzyme’s phosphatase activity, and is believed to be highly-disordered wh...
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| Udgivet i: | Biochim Biophys Acta Gen Subj |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317854/ https://ncbi.nlm.nih.gov/pubmed/30071273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2018.07.027 |
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