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More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation

Large portions of the genome undergo alternative pre-mRNA splicing in often intricate patterns. Alternative splicing regulation requires extensive control mechanisms since errors can have deleterious consequences and may lead to developmental defects and disease. Recent work has identified a complex...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Luco, Reini F, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317717/
https://ncbi.nlm.nih.gov/pubmed/21497503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.03.004
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