Application of Benchmark Concentration (BMC) Analysis on Zebrafish Data: A New Perspective for Quantifying Toxicity in Alternative Animal Models

Over the past decade, the zebrafish is increasingly being used as a model to screen for chemical-mediated toxicities including developmental toxicity (DT) and neurotoxicity (NT). One of the major challenges is lack of harmonization in data analysis approaches, thereby posing difficulty in comparing...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Sci
Main Authors: Hsieh, Jui-Hua, Ryan, Kristen, Sedykh, Alexander, Lin, Ja-An, Shapiro, Andrew J, Parham, Frederick, Behl, Mamta
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Ntp Neurotoxicology Screening Strategies Initiative
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317423/
https://ncbi.nlm.nih.gov/pubmed/30321397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy258
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