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Development and validation of a salivary tau biomarker in Alzheimer's disease

INTRODUCTION: Total tau (t-tau) and phosphorylated tau (p-tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau is also present in the salivary gland tissue and saliva, and salivary measures might produce an accurate, accessible, and...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Pekeles, Heather, Qureshi, Hamid Y., Paudel, Hemant K., Schipper, Hyman M., Gornistky, Mervyn, Chertkow, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317325/
https://ncbi.nlm.nih.gov/pubmed/30623019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.03.003
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