Sensitive and robust MALDI-TOF-MS glycomics analysis enabled by Girard's reagent T on-target derivatization (GTOD) of reducing glycans

Sensitive glycomics analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) is of great importance but significantly hampered by their low ionization efficiency and labile sialic acid moieties. Chemical derivatization offers a viable way to improve bot...

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Detalhes bibliográficos
Publicado no:Anal Chim Acta
Main Authors: Zhang, Ying, Wang, Bo, Jin, Wanjun, Wen, Yanan, Nan, Lijing, Yang, Mingming, Liu, Rendan, Zhu, Yuyang, Wang, Chengjian, Huang, Linjuan, Song, Xuezheng, Wang, Zhongfu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317096/
https://ncbi.nlm.nih.gov/pubmed/30598139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2018.10.015
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