Combination of Microwave-Assisted Girard Derivatization with Ionic Liquid Matrix for Sensitive MALDI-TOF MS Analysis of Human Serum N-Glycans

We developed a new method for MALDI-TOF MS detection of N-glycans derived from human serum. The synergistic combination of microwave-assisted Girard T derivatization, solid-phase extraction desalting, and an ionic liquid matrix (2, 5-dihydroxybenzoic acid/aniline) (GT-SPE-DHB/An) allowed of more sen...

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Bibliografiska uppgifter
I publikationen:J Anal Methods Chem
Huvudupphovsmän: Le, Hoa Thi, Park, Kyu H., Jung, Woong, Park, Hyung Soon, Kim, Tae Woo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215560/
https://ncbi.nlm.nih.gov/pubmed/30420937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7832987
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