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Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP(82–98)) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II
Background: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system. MS is a T cell-mediated disease characterized by the proliferation, infiltration, and attack of the myelin sheath by immune cells. Previous studies have shown that cyclization provides molecules with strict...
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| Publicado no: | Brain Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6316436/ https://ncbi.nlm.nih.gov/pubmed/30518150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci8120213 |
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