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Altered peptide ligands of myelin basic protein (MBP(87–99)) conjugated to reduced mannan modulate immune responses in mice

Mutations of peptides to generate altered peptide ligands, capable of switching immune responses from T helper 1 (Th1) to T helper 2 (Th2), are promising candidates for the immunotherapy of autoimmune diseases such as multiple sclerosis (MS). We synthesized two mutant peptides from myelin basic prot...

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Detalhes bibliográficos
Main Authors: Katsara, Maria, Yuriev, Elizabeth, Ramsland, Paul A, Tselios, Theodore, Deraos, George, Lourbopoulos, Athanasios, Grigoriadis, Nikolaos, Matsoukas, John, Apostolopoulos, Vasso
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792136/
https://ncbi.nlm.nih.gov/pubmed/19930042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03137.x
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