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Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration

Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Huntington’s disease (HD), are characterized by intracellular aggregation of proteins. In the case of ALS and FTD, these protein aggregates are found in the cytoplasm of affected neurons and c...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Fahrenkrog, Birthe, Harel, Amnon
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316434/
https://ncbi.nlm.nih.gov/pubmed/30486313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7120232
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