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Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration

Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Huntington’s disease (HD), are characterized by intracellular aggregation of proteins. In the case of ALS and FTD, these protein aggregates are found in the cytoplasm of affected neurons and c...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Fahrenkrog, Birthe, Harel, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316434/
https://ncbi.nlm.nih.gov/pubmed/30486313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7120232
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