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2′-O-Methylation of Ribosomal RNA: Towards an Epitranscriptomic Control of Translation?
Ribosomal RNA (rRNA) undergoes post-transcriptional modification of over 200 nucleotides, predominantly 2′-O-methylation (2′-O-Me). 2′-O-Methylation protects RNA from hydrolysis and modifies RNA strand flexibility but does not contribute to Watson-Crick base pairing. The contribution of 2′-O-Me to t...
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| Veröffentlicht in: | Biomolecules |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6316387/ https://ncbi.nlm.nih.gov/pubmed/30282949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8040106 |
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